XENICAL is a weight-loss drug marketed by Roche and sold under prescription as a medical remedy for obesity.
Like the famous Alli slimming pill, it contains the Orlistat molecule.
Consumer opinion is divided between those who consider it the only truly effective weight-loss drug, and those who accuse doctors of taking advantage of their patients’ desperation to prescribe it.
Is Xenical a real miracle pill or a dangerous drug to be avoided at all costs?
Should you ask your doctor to prescribe it, or opt for another, less radical option?
We’re going to find out the answers to these questions together in the following survey.
At the heart of the Xenical pill is the famous Orlistat molecule, an active substance which is a gastrointestinal lipase inhibitor.
Xenical is prescribed as part of a low-calorie diet with a maximum fat intake of 30%.
It is primarily intended for people suffering from obesity, to help them lose weight and maintain their new weight.
To understand how this pill works, we need to start by understanding what lipase is.
Lipase is a water-soluble enzyme involved in the combustion of ingested lipids, converting them into fatty acids available to the body.
By inhibiting lipase, Xenical reduces the quantity of lipids absorbed by the body during meals. Its main component, Orlistat, is said to reduce lipid absorption by 1/3.
Xenical is only prescribed to people with a BMI of 30 or more, in other words, who are obese in the purely medical sense of the term.
Exceptionally, and in specific, isolated cases, it is prescribed for people with a BMI equal to or greater than 27, but who also suffer from other risk factors such as type 2 diabetes, high blood pressure or high cholesterol.
As a reminder, BMI (Body Mass Index) is calculated by dividing weight in kilos by height in meters squared. So if you weigh 75 kilos and you’re 1.75m tall, your BMI is equal to : (1.75m x 1.75kg), or = 24.4.
Some doctors prescribe this product as part of their treatment for diabetes, enabling them to better control blood glucose levels should the usual treatment combined with diet and exercise prove insufficient.
Here are the results of a clinical study highlighting its effect on the condition of patients with type 2 diabetes: “XENODS study: Xenical in the prevention of diabetes in obese subjects.”
(Source: Department of Body Composition and Metabolism, Sahlgrenska University Hospital, Göteborg, Sweden. Torgerson JS, Hauptman J, Boldrin MN, Sjöström L. Diabetes Care. 2004 Jan; 27(1): 155-61).
What is the dosage of Xenical?
The first thing to remember when taking Xenical is to follow your prescribing physician’s instructions.
It’s very important to stick to the dose prescribed by your practitioner, especially as overdosing can lead to very serious side effects.
The recommended dose is 120 mg taken 3 times a day, spread over the 3 main meals, at mealtime or no later than one hour afterwards.
As Xenical selectively attacks fat metabolism, if you’ve skipped a meal, or if the meal you’ve eaten is very low in fat, taking this pill will have no effect.
It’s worth remembering that a number of other factors, specific to each individual case, can determine the ideal dose of Xenical recommended for each person: starting weight, presence of other risk factors, other medications taken in parallel…
For all these reasons, we stress the need to follow your doctor’s instructions to the letter, and to use Xenical as part of a medical follow-up program.
If you ever forget to take your pill, and there’s still time before the next dose, you can choose between taking your forgotten tablet or not taking it at all, and continuing to take the rest of your treatment regularly. But under no circumstances should you take two pills at once if you forget – never!
Xenical must be combined with a low-calorie diet prescribed by your doctor alone. Adherence to this diet is essential to achieve the desired results.
Ingredients of Xenical pills
Xenical pills are turquoise in color. Each pill contains 120 mg orlistat and other inactive components, including:
1. MICROCRYSTALLINE CELLULOSE ;
2. GELATIN ;
3. INDIGO CARMINE ;
4. SODIUM STARCH GLYCOLATE ;
5. SODIUM LAURYL SULFATE ;
6. TITANIUM DIOXIDE ;
7. POLYVIDONE K30 ;
Contraindications of Xenical
Xenical is contraindicated in the following cases (Don’t worry, your doctor will take this into account before prescribing this medicine):
- Allergy to any of the components of Xenical ;
- Cholestasis: failure of the liver to produce bile;
- Malabsorption syndrome: problems with absorption of nutrients from the diet;
- breast-feeding and pregnancy.
However, if you are taking any other medication at the same time, or have any other medical complication, whether treated or not, you must inform your doctor, as Xenical can interfere with a wide range of medications.
Side effects of Xenical
Even if you take Xenical in accordance with your doctor’s instructions, there is a risk that you may develop side effects.
Many of the effects listed below have been reported by users during the first few weeks of taking Xenical. After this period, these effects may persist for some people, and disappear for others. Always consult your doctor if you notice any abnormal effects.
List of some of the most common Xenical side effects:
- Skin allergy;
- Difficulty breathing ;
- Continuous epigastric pain;
- Continued feeling of weakness and fatigue;
- Considerable loss of appetite;
- Nausea and vomiting;
- Change in color of urine and stools.
This list includes the most notable side effects, but be aware that there are some “minor” side effects reported by other patients taking Xenical. These can include transient migraines, repeated gas emissions, rectal pain and even menstrual irregularities…
Is Xenical effective?
Apart from its contraindications and undesirable side effects, Xenical could be of considerable help to obese people.
In fact, it has been the subject of 5 comparative clinical studies. Some pre-marketing clinical tests showed weight loss of 5-10% in 2 weeks.
Other tests revealed that during the first 3 months of Xenical treatment, some 70% of subjects lost 3 times more weight, compared with those who just followed a diet.
Finally, some clinical studies have suggested that 20% of obese people who took part in these studies managed to lose 10% of their weight after taking Xenical for a year.
It is therefore highly probable that the variation in results is a direct consequence of the differences in patients’ bodies and the hypocaloric diet associated with taking Xenical.
In fact, people in the same situation, following the same diet and taking a placebo instead of Xenical, were able to lose 8% of their weight.
Where to buy Xenical and at what price
Despite everything that’s been said about Xenical, it’s still available over the counter online. In the course of our research, we found these offers on this Swiss site specializing in the sale of slimming products.
Note that if you don’t have a prescription, the site in question will ask you to answer a series of questions in order to grant or refuse you an online prescription? The product is packaged as follows:
- Box of 252 pills 120mg dose;
- Box of 168 pills 120mg pills;
- Box of 84 pills 120mg pills.
Delivery is free, and the site in question has all the hallmarks of trust (including a telephone number available to customers).
Our Opinion on Xenical
Xenical potentially has a definite slimming effect on obese subjects.
If you are willing to follow a strict hypocaloric diet and closely control your lipid intake, it could be a major help. However, we advise you to combine this treatment with a diet and exercise program, to optimize your results.
If your health condition does not allow you to use Xenical, browse our site to find out about other non-prescription weight-loss supplements that can be effective and safe.